New Research Spotlight

New Research Spotlight

Keeping You Up to Date on New Research Impacting Your Practice
This series is exclusively available to IPSIS members to help you stay informed of important new research that may impact your practice.

West T, Hussain N, Bhatia A, et al.

Pain intensity and opioid consumption after temporary and permanent peripheral nerve stimulation: a 2-year multicenter analysis.
Reg Anesth Amp Pain Med. Published online July 26, 2024:rapm-2024-105704. doi:10.1136/rapm-2024-105704

Reviewed by: Matt Kaufman, MD, and Jeremy Beckworth, MD

  • October 2024
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Playfair D, Smith A, Burnham R.

An evaluation of the effectiveness of platelet rich plasma epidural injections for low back pain suspected to be of disc origin – A pilot study with one-year follow-up.
Interventional Pain Medicine 2024; 3.100403. 10.1016/j.inpm.2024.100403.

Reviewed by: Kevin Barrette, MD, MBA and Charles Odonkor, MD, MA

  • September 2024
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Miller A, Candido KD, Knezevic NN, et al.

A randomized, placebo-controlled trial of long-acting dexamethasone viscous gel delivered by transforaminal injection for lumbosacral radicular pain.
Pain. Published online June 14, 2024. doi:10.1097/j. pain.0000000000003287

Reviewed by: Anthony Schwarzer, MB BS, MMed, PhD and Andrew Stephens, MD

  • August 2024
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Ferch RD, Zhang T, Bogduk N.

Arthrodesis of the lateral atlanto-axial joint for the relief of neck pain and cervicogenic headache.
Pain Med 2024;25(3):203-210. doi:10.1093/pm/pnad153

Reviewed by: Josh Levin, MD and Reza Ehsanian, MD, PhD

  • August 2024
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Staats PS, Dorsi MJ, Reece DE, Strand NH, Poree L, Hagedorn JM.

Percutaneous image-guided lumbar decompression and outpatient laminectomy for the treatment of lumbar spinal stenosis: a 2-year Medicare claims benchmark study.
Interventional Pain Medicine 2024 June;3(2):100412. https://doi.org/10.1016/j.inpm.2024.100412

Reviewed by: Chris Radlicz, DO and Roya Moheimani, MD

  • July 2024
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Ehsanian R, Wu V, Grandhe R, Valeriano M, Petersen TR, Rivers WE, Koshkin E.

A single-center real-world review of 10 kHz high-frequency spinal cord stimulation outcomes for treatment of chronic pain.
Interventional Pain Medicine 2024;3(1):100402. https://doi.org/10.1016/j.inpm.2024.100402

Reviewed by: Christine Hunt, DO and Chris Radlicz, DO

  • June 2024
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Tran J, Campisi E, Roa Agudelo A, Agur AM, Loh E.

High-fidelity 3D modelling of the lumbar dorsal rami
Interventional Pain Medicine 2024; 3(1),100401. https://doi.org/10.1016/j.inpm.2024.100401

Reviewed by: W. Evan Rivers, DO and Shaima Khandaker, MD

  • April 2024
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Panagopoulos J, Magnussen JS, Hush J, et al.

Prospective Comparison of Changes in Lumbar Spine MRI Findings over Time between Individuals with Acute Low Back Pain and Controls: An Exploratory Study
AJNR Am J Neuroradiol. 2017;38(9):1826-1832. doi:10.3174/ajnr.A5357

Reviewed by: Vance Lehman, MD and John Keel, MD

  • March 2024
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Guven Kose S, Kirac Unal Z, Kose HC, Celikel F, Akkaya OT.

Ultrasound-guided genicular nerve radiofrequency treatment: prospective randomized comparative trial of a 3-nerve protocol versus a 5-nerve protocol
Pain Med 2023;24(7):758-767. doi: 10.1093/pm/pnad025

Reviewed by: Taylor Burnham, DO, MS and Matthew Kaufman, MD

  • February 2024
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Caragea M, Woodworth T, Curtis T, Blatt M, Cheney C, Brown T, Carson D, Kuo
KT, Randall D, Huang EY, Carefoot A, Teramoto M, Mills M, Cooper A, Burnham T, Conger A, McCormick ZL.

Genicular nerve radiofrequency ablation for the treatment of chronic knee joint pain: a real-world cohort study with evaluation of prognostic
Pain Med 2023;24(12):1332-1340. doi: 10.1093/pm/pnad095. PMID: 37428157.

Reviewed by: Charles Odonkor, MD and Fransoua Her, MD, PhD

  • January 2024
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Caragea M, Le A, Curtis T, Ni A, Clark T, Joyce A, Hickman C, Lawrence B, Randell Z, Goodman P, Poduska A.

Does medial branch radiofrequency neurotomy accelerate degenerative lumbar spondylolisthesis compared to natural progression? A cross- sectional cohort study
Interventional Pain Medicine 2023;2(4):100289.

Reviewed by: Jeremy Beckworth, MD and Kevin Barrette, MD

  • December 2023
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Landers MH, Newton F, Alvarado M, Bogduk N.

Comparing the effectiveness of lumbar medial branch radiofrequency coagulation using 18-gauge and 16-gauge cannulae
Interventional Pain Medicine 2023; 2(4). doi:10.1016/j.inpm.2023.100279

Reviewed by: Reza Ehsanian, MD, PhD and Joshua Levin, MD

  • November 2023
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Rebbeck T, Bandong AN, Leaver A, et al.

Implementation of a risk-stratified, guideline-based clinical pathway of care to improve health outcomes following whiplash injury (Whiplash ImPaCT): a multicentre, randomized, controlled trial
Pain 2023;164(10):2216-2227.

Reviewed by: Anthony Schwarzer, MBBS, PhD and Christine Hunt, DO, MS

  • October 2023
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Filiatrault K, Mares C, Filiatrault M, Levasseur M, Chang M, Denis I.

Randomized controlled trial comparing technical features in clinical efficacy of multi-tined cannula versus a conventional cannula for cervical medial branch radiofrequency neurotomy and chronic neck pain
Interventional Pain Medicine 2023 (2). doi.org/10.1016/j. inpm.2023.100272

Reviewed by: Evan Berlin, MD and Vance Lehman, MD

  • September 2023
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Jones CMP, Day RO, Koes BW, Latimer J, Maher CG, McLachlan AJ, Billot L, Shan S, Lin CC; OPAL Investigators Coordinators.

Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial
Jul 22;402(10398):304-312. doi: 10.1016/S0140-6736(23)00404-X. Epub 2023 Jun 28. PMID: 37392748.

Reviewed by: Byron Schneider, MD and W. Jeremy Beckworth, MD

  • August 2023
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Fischgrund, JS, Rhyne, A, Macadaeg, K. et al.

Long-term outcomes following intraosseous basivertebral nerve ablation for the treatment of chronic low back pain: 5-year treatment arm results from a prospective randomized double-blind sham- controlled multi-center study
Eur Spine J 2020;29(8):1925-1934. doi:10.1007/s00586- 020-06448-x

Reviewed by: Fransoua Her, MD, PhD and Taylor Burnham, DO, MS

  • August 2023
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Chalermkitpanit P, Pannangpetch P, Kositworakitkun Y, Singhatanadgige W, Yingsakmongkol W, Pasuhirunnikorn P, Tanasansomboon T.

Ultrasound-guided pulsed radiofrequency of cervical nerve root for cervical radicular pain: a prospective randomized controlled trial.
Spine J 2023 May;23(5):651-655. Doi: 10.1016/j. spinee.2023.01.004. Epub 2023 Jan 12. PMID: 36641034

Reviewed by: Josh Levin, MD and Anthony Schwarzer, MB BS, PhD, MMed

  • July 2023
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Maeda M, Maeda N, Masuda K, Nagano T, Tanaka Y.

Ultrasound-guided cervical intervertebral disc injection without fluoroscopy.
J Ultrasound Med 2023;42(1):239-246. doi:10.1002/jum.15989.

Reviewed by: David Levi, MD and W. Evan Rivers, DO

  • May 2023
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Vallejo R, Benyamin R, Orduna-Valls J, et al.
A randomized controlled study of the long-term efficacy of cooled and monopolar radiofrequency ablation for the treatment of chronic pain related to knee osteoarthritis.

Interventional Pain Medicine 2(2023).

Reviewed by: Christine Hunt, DO and Charles Odonkor, MD

  • April 2023
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Spirig JM, HΓΌllner M, Cornaz F, et al.
[18F]-sodium fluoride PET/MR for painful lumbar facet joint degeneration - a randomized controlled clinical trial.

Spine J. 2022;22(5):769-775. doi:10.1016/j.spinee.2021.11.014

Reviewed by: Vance Lehman, MD and Evan Berlin, MD

  • March 2023
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Kapural L, Minerali A, Sanders M, Matea M, Dua S.
Cooled Radiofrequency Ablation Provides Prolonged Pain Relief Compared to Traditional Radiofrequency Ablation: A Real-World, Large Retrospective Clinical Comparison from a Single Practice.

Pain Res. 2022 Aug 31;15:2577-2586. doi: 10.2147/JPR.S373877. PMID: 36068792; PMCID: PMC9441169

Reviewed by: Jeremy Beckworth, MD and Yeng F. Her, MD, PhD

  • February 2023
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Celenlioglu AE, Sir E.
Predictive factors affecting treatment success in ganglion impar block applied in chronic coccygodynia.

Reg Anesth Pain Med. 2022 Jun 23:rapm-2022-103582. doi: 10.1136/rapm-2022-103582. Epub ahead of print. PMID: 35738667.

Reviewed by: Taylor Burnham, DO, MS and Josh Levin, MD

  • January 2023
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Hara S, Andresen H, Solheim O, et al.
Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial.

JAMA. 2022;328(15):1506-1514. doi:10.1001/jama.2022.18231

Reviewed by: Reza Ehsanian, MD, PhD and Byron J. Schneider, MD

  • December 2022
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Nolan III JE, Sundet AD, Kagan BD, Lake TJ, Krag MH, Lunardini DJ.
The positive prediction of single photon emission computed tomography/computed tomography (SPECT/CT) in the outcome of intervention for cervical facet pain.

Spine J. 2022;22(10):1622-1627. doi:10.1016/j.spinee.2022.04.021.

Reviewed by: Charles A. Odonkor, MD, MA and David Levi, MD

  • November 2022
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Rittenberg JD, Air ME, Schmittdiel JA, Horton BH, Greenlund LS, Maus TP, Sytsma TT.
Spinal corticosteroid injections are not associated with increased influenza risk.

Spine J. 2022 Jul;22(7):1106-1111. doi: 10.1016/j.spinee.2022.02.006. Epub 2022 Feb 15. PMID: 35181540.

Reviewed by: Jeremy Beckworth, MD and Evan Rivers, DO

  • October 2022
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Schneider B, Joshi M, Ehsanian R, McCormick Z, Patel J, Zheng P, Nagpal.
Patient-perceived duration of effect of lidocaine and bupivacaine following diagnostic medial branch blocks: a multicenter study.

Interventional Pain Medicine 2022;1(2).

Reviewed by: Evan Berlin, MD and Vance Lehman, MD

  • September 2022
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Tran J, Peng P, Loh E.
Anatomical study of the medial branches of the lumbar dorsal rami: implications for image-guided intervention.

Reg Anesth Pain Med. 2022 May 19:rapm-2022-103653.

Reviewed by: Christine Hunt, DO and Jeremy Beckworth, MD

  • August 2022
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Eldabe S, Duarte RV, Gulve A, Thomson S, Baranidharan G, Houten R, Jowett S, Sandhu H, Chadwick R, Brookes M, Kansal A, Earle J, Bell J, Robinson J, Walker S, Rhodes S, Taylor RS.
Does a screening trial for spinal cord stimulation in patients with chronic pain of neuropathic origin have clinical utility and cost-effectiveness (TRIAL-STIM)? A randomised controlled trial.

Pain. 2020 Dec;161(12):2820-2829.

Reviewed by: Ryan S. D’Souza, MD and Taylor Burnham, DO, MS

  • July 2022
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Burnham T, Clements N, Conger A, et al.
A comparison of the effectiveness of cervical medial branch radiofrequency ablation for chronic facet joint syndrome in patients selected by two common medial branch block paradigms.

Interventional Pain Medicine 2022;1(2). ISSN 2772-5944.

Reviewed by: W. Evan Rivers, DO and Anthony Schwarzer, MBBS, PhD

  • June 2022
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Schultz DM, Hagedorn JM, Abd-Elsayed A, Stayner S.
Safety of Interlaminar Cervical Epidural Injections: Experience With 12,168 Procedures in a Single Pain Clinic.

Pain Physician. 2022 Jan;25(1):49-58. PMID: 35051144.

Reviewed by: David Levi, MD and Nida Fatima, MD, MBBS

Zhang H, Yang B, Hao D, et al.
New Research Spotlight: Pain Location Is Associated with Fracture Type in Acute Osteoporotic Thoracolumbar Vertebral Fracture: A Prospective Observational Study.
Pain Med. 2022;23(2):263-268. doi:10.1093/pm/pnab229

Reviewed by: Vance Lehman, MD and Reza Ehsanian, MD, PhD

Manchikanti L, Kosanovic R, Pampati V, Sanapati MR, Hirsch JA.
Outcomes of Cervical Therapeutic Medial Branch Blocks and Radiofrequency Neurotomy: Clinical Outcomes and Cost Utility are Equivalent.
Pain Physician. 2022;25(1):35-47.

Reviewed by: Joe Lee, MD and David A. Edwards, MD, PhD

Perez J, Gofeld M, Leblang S, Hananel A, Aginsky R, Chen J, Aubry JF, Shir Y.
Fluoroscopy-Guided High-Intensity Focused Ultrasound Neurotomy of the Lumbar Zygapophyseal Joints: A Clinical Pilot Study
.
Pain Med. 2022 Jan 3;23(1):67-75. doi: 10.1093/pm/pnab275. PMID: 34534337; PMCID: PMC8723143

Reviewed by: W. Jeremy Beckworth, MD and Evan Berlin, MD

  • February 2022

Chen AS, Solberg J, Smith C, et al.
Intraarticular Platelet Rich Plasma vs Corticosteroid Injections for Sacroiliac Joint Pain-a Double Blinded, Randomized Clinical Trial
.
[published online ahead of print, 2021 Nov 24]. Pain Med. 2021; pnab332. doi:10.1093/pm/pnab332.

Reviewed by: Taylor Burnham, DO, MS and Christine Hunt, DO, MS

Groh AMR, Fournier DE, Battie MC, Seguin CA.
Innervation of the Human Intervertebral Disc: A Scoping Review.

Pain Medicine 2021;22:1281-1304.

Reviewed by: Anthony Schwarzer, MB BS, PhD and Ryan D’Souza, MD

  • December 2021

Thomson S, Chawla R, Love-Jones S, Sharma M, Vajramani G, Williams A, Eldabe S.
Restorative Neurostimulation for Chronic Mechanical Low Back Pain: Results from a Prospective Multi-centre Longitudinal Cohort.

Pain and Therapy 2021:1-5. Trial Registration: ClinicalTrials.gov Identifier: NCT01985230.

Reviewed by: Charles Odonkor, MD, MA and W. Evan Rivers, DO

  • November 2021

Petersen EA, Stauss TG, Scowcroft JA, et al.
Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial.

JAMA Neurol. 2021;78(6):687–698. doi:10.1001/jamaneurol.2021.0538

Reviewed by: Nathaniel Schuster, MD and Joe Lee, MD

Disclaimer:
The reviews presented above have been completed by EBM-trained members of the IPSIS Research Division and represent the thoughts and opinions of the individuals who have completed the reviews, not the IPSIS Research Division or IPSIS as an organization. The intent of the New Research Spotlight is to summarize and critique recently published studies on high priority topics to encourage consideration by IPSIS members
.